is it normal to feel nothing at all on BPC? week 3

J
Joined 2026
32 posts
4/13/2026 · 411 views

running for a chronic SI joint thing, 500mcg/day split, week 3, zero change. do I give up or push to 6 weeks?

6 Replies

H
Joined 2025
212 posts
hexaclinicContributor
4/12/2026

Agree with tendon_theory. What's your diagnosis — actual sacroiliitis, or "SI pain" as a catchall? If it's mechanical/stability, PT for glutes + core is doing more than any peptide will.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
T
Joined 2025
52 posts
4/12/2026

3 weeks is early. Push to 6. SI joint stuff is also weird because the "joint" isn't really healing in the same way a tendon does — chronic SI pain is often stability/mechanical rather than tissue damage. BPC may not be the right tool for this goal.

Pulley A2
  • BPC-157 · 250 mcg · 2x/day local · sub-Q
  • TB-500 · 2 mg · weekly · sub-Q
J
Joined 2026
32 posts
4/13/2026

haven't had a real workup tbh. just been calling it SI pain for years. fair point, maybe worth seeing someone before throwing more compounds at it.

S
Joined 2026
117 posts
4/13/2026

"BPC isn't doing anything" is often a sign that the problem isn't what we think it is. Good instinct to pause and diagnose.

B
Joined 2026
13 posts
4/15/2026

been there on SI stuff. ended up being a glute med weakness that PT fixed in 10 weeks, no peptides required. fingers crossed for you.

Q
Joined 2025
31 posts
15d ago

Yeah honestly SI stuff is frustrating because half the time it's not actually damaged tissue, it's just unstable or your pelvis is tilted weird. I ran BPC for like 4 weeks thinking I had tendinitis in my hip and nothing changed, then got an actual MRI and turns out I just needed to stop sitting like a slob and do some dead bugs. Worth getting imaging done before you waste more time on it.

Nightshift
  • DSIP · 100 mcg · pre-bed · sub-Q
  • Epithalon · 10 mg · 10d cycles · sub-Q
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