Liver enzymes during a long TB-500 cycle
26 posts
Quick anecdote and looking for confirmation. 16 weeks of TB-500 (2.5mg loading x4 weeks, 2mg/wk maintenance). Pulled LFTs at baseline, week 8, week 16.
- AST: 22 -> 27 -> 26 U/L
- ALT: 24 -> 32 -> 30 U/L
- ALP: 74 -> 78 -> 73
- GGT: 18 -> 21 -> 19
All in range the whole time but ALT is trending a touch up at the 8-week mark then stable. Training didn't change, no new supplements, no alcohol uptick.
Is this real or noise? Anyone else tracked LFTs through long TB cycles?
6 Replies
27 posts
ALT 24 -> 32 is about 33% which sounds big but is inside within-person CV for ALT (~15-25%) plus the small n. Alone I wouldn't read anything into it. Also, ALT is sensitive to RECENT training — if you trained hard in the 72h before the draw it'll be 10-20% higher just from that.
- Sermorelin · 300 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
26 posts
50 posts
Also pull CK alongside LFTs next time. If CK is elevated, the ALT bump is muscle not liver. Clean way to disambiguate.
50 posts
I've done 2 long TB cycles (12 and 14 weeks) with LFTs pulled, rest-adjusted, and neither showed any real liver signal. Anecdotal consensus seems to be TB is not hepatotoxic at these doses.
- BPC-157 · 250 mcg · 2x/day local · sub-Q
- TB-500 · 2 mg · weekly · sub-Q
17 posts