Fasting insulin and HOMA-IR on CJC/Ipa

Same shape on my data last year. Insulin plateaued at ~8, HOMA-IR ~1.85, stayed there for 3 more months. Cycled off for 6 weeks, insulin dropped back to 5.1.

The plateau is not a slow-motion metabolic breakdown, it's the new homeostasis.

The plateau is real — fasting insulin tends to hit a new equilibrium 3-4 months into a GHRP stack and stabilize unless you're pushing the dose. If HbA1c stays under 5.5 I'd ride it another 2 months.

If a1c crosses 5.6 I'd cycle off.

a1c is really the deciding vote. Get that reading and retest again at month 6. If it's stable under 5.5 you're fine.

Nice clean monotonic dataset. Your month-0 to month-4 jump is clearly outside CV (which is ~8-12% for fasting insulin at low baselines). Real signal, not noise.

Your IGF-1 response + modest insulin creep is basically a green light. Plenty of people trade a HOMA-IR of 1.0 for 1.8 in exchange for IGF-1 +80. That's a reasonable trade if you're tracking and not just flying blind.

a1c back — 5.2 -> 5.4. Going to ride it another 6 weeks and retest.

Good call. Sane decision framework throughout this thread, honestly.

yeah this is solid data honestly. the a1c staying that low is the key thing, anything under 5.5 and you're not really in danger territory. my question would be whether the insulin creep levels off or keeps climbing though, like is month 5 gonna be 8.5 or does it actually plateau at 7.8? that's what id wanna know before committing to another 6 weeks