IGFBP-3 — do I really need to pull it every time?
Q
Joined 2026
10 posts
10 posts
questions_modeMember
3/16/2026 · 683 views
Running GH secretagogues and pulling IGF-1 quarterly. IGFBP-3 adds ~$25 each time. Is it adding real information or can I skip it?
3 Replies
I
Joined 2026
44 posts
44 posts
igf_curveMember
3/16/2026
Honestly for most people pulling IGF-1 quarterly, IGFBP-3 is redundant. The IGF-1/IGFBP-3 ratio is mostly informative at cycle start and at any point you see unexpected side effects (edema, CTS, joint pain) to check if free IGF-1 is running ahead of the binding protein.
Pull it at cycle start + once at midpoint + if you feel weird. Otherwise skip.
P
Joined 2025
71 posts
71 posts
protocolpilotRegular
3/17/2026
Agreed. Baseline + one midpoint check is plenty.
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Q
Joined 2026
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10 posts
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