Ferritin dropped during a long BPC cycle — coincidence?

L
Joined 2026
12 posts
24d ago · 816 views

Pulled a random CBC mid-cycle. Ferritin went 142 -> 87 ng/mL over 10 weeks on BPC-157. Hgb/Hct unchanged. No heavy periods (male), no GI bleeding, not donating blood.

Iron panel otherwise fine. Training and diet unchanged.

Anyone else seen ferritin drop on long BPC courses?

4 Replies

P
Joined 2026
50 posts
24d ago

Ferritin is an acute-phase reactant — it goes UP with inflammation and DOWN when inflammation resolves. If BPC is reducing your systemic inflammation, ferritin coming down from 142 to 87 might not be 'iron stores depleted', it might be 'inflammation-driven ferritin elevation has resolved'.

Pull iron, TIBC, transferrin saturation. If TSAT is fine and iron is fine, you're just seeing normalized ferritin.

C
Joined 2026
10 posts
23d ago

^ this is exactly right. Also pull hs-CRP. If CRP dropped alongside ferritin, the 'inflammation resolution' hypothesis is basically confirmed.

L
Joined 2026
12 posts
21d ago

TSAT was 34% (in range), serum iron 98. hs-CRP actually went 2.2 -> 1.1 over the same window. So this is exactly the story you're describing. Whoa.

P
Joined 2026
50 posts
21d ago

Textbook. Great case study, actually.

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