BPC-157 and blood thinners — has anyone here actually been on both?
22 posts
Not looking for medical advice, I'll talk to my actual doctor. Looking for experience reports.
On apixaban (Eliquis) long-term after a DVT. Lifting shoulder flared badly 3 months ago and I've been eyeing BPC. The only thing I've seen referenced is Sikiric's angiogenesis work — the theory being BPC promotes vascular growth/repair, which in a patient on anticoagulation is not obviously bad but is also not obviously fine.
Has anyone here actually run BPC while on a DOAC or warfarin? Any injection-site bruising, any hematology weirdness, any conversation with your prescriber about it?
To be clear — I understand the answer might be 'don't.' Just trying to hear real experience rather than internet theorizing.
10 Replies
122 posts
Not your doctor. But: the main practical concern with BPC on any anticoagulant is injection-site hematoma from the pin itself, not the peptide. Sub-Q insulin pins leave pinpoint bleeds — on a DOAC those can be a bit more noticeable. Use 31g if you can, compress for a full minute post-pin, rotate sites aggressively.
212 posts
Ran BPC for 6 weeks while on apixaban post-PE. No issues. My hematologist's position was basically 'I don't know what BPC does, but I don't see a mechanistic reason it would interact with apixaban.' Mild increased bruising at pin sites, nothing clinically meaningful. Your mileage may vary.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
22 posts
@hexaclinic this is exactly the experience report I was looking for. Thank you. Did you tell the hematologist upfront or was it a 'by the way' thing?
212 posts
@late_bloomer_m upfront. I don't hide anything from prescribers. Worst case they say no and you reconsider. Best case you get a real professional opinion to factor in.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
117 posts
The angiogenesis story for BPC is a mechanism hypothesis, not a documented clinical interaction. I wouldn't assume it's additive with anticoagulation in a meaningful way. But the bruising point from dr_doubt is real — that's the concrete concern.
71 posts
This is one of the threads where 'talk to your doctor' is not a copout — the interaction space is genuinely unknown and the consequences of a surprise are serious.
53 posts
Flagging for visibility. Blood thinner threads are exactly where I'd want everyone to default to caution. Real experience reports are welcome, blanket 'yeah just run it' replies are not.
- Sermorelin · 200 mcg · 5x/wk AM · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
22 posts
Appreciated everyone. Talking to hematology next week. Will report back if they greenlight and I actually run it.
24 posts
honestly the "unknown interaction" thing gets overstated. BPC isn't some exotic mystery compound anymore, tons of people run it, and I'd bet a solid chunk of folks on blood thinners have tried it without drama and just never posted about it. the ones who had problems are louder. that said if you're on apixaban specifically for a DVT then yeah, your hematologist has more skin in the game than usual so might as well ask them instead of guessing.
68 posts
ran it for like 6 weeks while on warfarin, subq into delts. zero bruising that stood out from normal pin marks, no bleeding issues or anything weird. that said i wasnt doing any heavy shoulder work at the time so can't really speak to your situation specifically.
- Epithalon · 10 mg · 10d on / 80d off · sub-Q
- MOTS-c · 5 mg · 2x/wk · sub-Q
- 5-Amino-1MQ · 150 mg · daily · oral