Hair loss stack — GHK-Cu + AHK-Cu + zinc thymulin. Anyone actually doing all three?

G
Joined 2026
22 posts
2/20/2026 · 2215 views

I've been on topical minoxidil + finasteride for two years and it's holding the line but not regrowing much. Looking at adding the copper peptide trio you see on r/tressless:

  • GHK-Cu — fibroblast / follicle stem cell signaling
  • AHK-Cu — dermal papilla stimulation, sometimes marketed as 'stronger for hair than GHK'
  • Zinc thymulin — separate mechanism, seems to slow miniaturization in some data

Questions:

  1. Is the AHK-Cu claim real or is it just GHK-Cu's cousin with better marketing?
  2. Anyone running all three topically? Do you mix into one serum or rotate?
  3. Timing with min/fin — same application, or separate?
  4. 6+ month results appreciated. I'm tired of 'week 3 looking promising!' posts.

12 Replies

R
Joined 2025
36 posts
2/20/2026

Been running GHK-Cu + zinc thymulin for a year. Skipped AHK-Cu because I've never seen convincing comparison data — it's structurally similar and almost all the 'AHK is better for hair' claims trace back to one supplier's white paper. I'd pick GHK-Cu.

Current
  • Tesamorelin · 1 mg · daily AM · sub-Q
F
Joined 2026
23 posts
2/21/2026

I layer min (5% + tret 0.025% combined) in the morning, GHK-Cu 0.2% at night. Zinc thymulin goes on nights I skip tret. 8 months in, hairline hasn't moved and I'm getting vellus on the temples. Can't isolate which is doing what.

T
Joined 2025
58 posts
theoreticRegular
2/21/2026

AHK-Cu has some in-vitro dermal papilla work but the human topical evidence is much thinner than GHK-Cu. Run GHK-Cu and zinc thymulin, drop AHK unless you have money to burn.

Longevity
  • Epithalon · 10 mg · 10d on / 80d off · sub-Q
  • MOTS-c · 5 mg · 2x/wk · sub-Q
  • 5-Amino-1MQ · 150 mg · daily · oral
G
Joined 2026
22 posts
2/22/2026

@hexaclinic this is the kind of detail I needed. Thank you.

H
Joined 2025
205 posts
hexaclinicContributor
2/23/2026

Important: don't apply copper peptides at the same time as minoxidil. The minoxidil vehicle (prop glycol, ethanol) wrecks the copper complex. Space them by 4+ hours or apply on opposite schedules.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
C
Joined 2025
41 posts
2/23/2026

Stay on the min/fin. The copper peptides are at best additive, not replacements. Anyone telling you otherwise is selling something.

W
Joined 2026
17 posts
2/26/2026

Is the zinc thymulin the stuff that has to be freshly compounded each time? I keep reading it's unstable.

P
Joined 2026
50 posts
2/26/2026

@wanderlite yes, it's notoriously unstable in solution. Either you buy single-use vials or you reconstitute small batches and use within a couple weeks refrigerated. That's the real barrier to running it.

S
Joined 2026
6 posts
silentscrollNew Member
2/27/2026

Reading. 3 years on fin, considering copper peptides. Useful thread.

S
Joined 2026
115 posts
3/2/2026

The original Pickart hair work on GHK-Cu is worth reading before you commit. Small trials, reasonable effect size, much less hype than the modern social media version.

P
Joined 2026
32 posts
3/5/2026

Can women run this stack? Asking because most hair loss threads default to male pattern.

R
Joined 2025
36 posts
3/5/2026

@petal_push GHK-Cu and zinc thymulin are fine for women topically. Finasteride is where the conversation changes. The copper peptides don't have the same hormone pathway concerns.

Current
  • Tesamorelin · 1 mg · daily AM · sub-Q
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