Hair loss stack — GHK-Cu + AHK-Cu + zinc thymulin. Anyone actually doing all three?
25 posts
I've been on topical minoxidil + finasteride for two years and it's holding the line but not regrowing much. Looking at adding the copper peptide trio you see on r/tressless:
- GHK-Cu — fibroblast / follicle stem cell signaling
- AHK-Cu — dermal papilla stimulation, sometimes marketed as 'stronger for hair than GHK'
- Zinc thymulin — separate mechanism, seems to slow miniaturization in some data
Questions:
- Is the AHK-Cu claim real or is it just GHK-Cu's cousin with better marketing?
- Anyone running all three topically? Do you mix into one serum or rotate?
- Timing with min/fin — same application, or separate?
- 6+ month results appreciated. I'm tired of 'week 3 looking promising!' posts.
14 Replies
43 posts
Been running GHK-Cu + zinc thymulin for a year. Skipped AHK-Cu because I've never seen convincing comparison data — it's structurally similar and almost all the 'AHK is better for hair' claims trace back to one supplier's white paper. I'd pick GHK-Cu.
- Tesamorelin · 1 mg · daily AM · sub-Q
24 posts
I layer min (5% + tret 0.025% combined) in the morning, GHK-Cu 0.2% at night. Zinc thymulin goes on nights I skip tret. 8 months in, hairline hasn't moved and I'm getting vellus on the temples. Can't isolate which is doing what.
68 posts
AHK-Cu has some in-vitro dermal papilla work but the human topical evidence is much thinner than GHK-Cu. Run GHK-Cu and zinc thymulin, drop AHK unless you have money to burn.
- Epithalon · 10 mg · 10d on / 80d off · sub-Q
- MOTS-c · 5 mg · 2x/wk · sub-Q
- 5-Amino-1MQ · 150 mg · daily · oral
25 posts
212 posts
Important: don't apply copper peptides at the same time as minoxidil. The minoxidil vehicle (prop glycol, ethanol) wrecks the copper complex. Space them by 4+ hours or apply on opposite schedules.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
43 posts
Stay on the min/fin. The copper peptides are at best additive, not replacements. Anyone telling you otherwise is selling something.
24 posts
Is the zinc thymulin the stuff that has to be freshly compounded each time? I keep reading it's unstable.
51 posts
@wanderlite yes, it's notoriously unstable in solution. Either you buy single-use vials or you reconstitute small batches and use within a couple weeks refrigerated. That's the real barrier to running it.
8 posts
117 posts
The original Pickart hair work on GHK-Cu is worth reading before you commit. Small trials, reasonable effect size, much less hype than the modern social media version.
36 posts
Can women run this stack? Asking because most hair loss threads default to male pattern.
43 posts
@petal_push GHK-Cu and zinc thymulin are fine for women topically. Finasteride is where the conversation changes. The copper peptides don't have the same hormone pathway concerns.
- Tesamorelin · 1 mg · daily AM · sub-Q
68 posts
been lurking this sub for like 3 weeks and the copper peptide stuff keeps showing up. main thing holding me back is im not sure if im actually seeing results or just placebo because hair takes forever to evaluate. also the stability issue is making me hesitant, dont wanna pay for something thats gonna degrade in my bathroom. has anyone actually stuck with this for a full year and seen something worth the effort or nah
- Epithalon · 10 mg · 10d on / 80d off · sub-Q
- MOTS-c · 5 mg · 2x/wk · sub-Q
- 5-Amino-1MQ · 150 mg · daily · oral
29 posts
Ran GHK and AHK for like 4 months topical, mixed em together. Honestly the difference between the two is probably overstated, they work on similar pathways. Stability is legit a concern tho, keep it in the fridge and dont let it sit in your bathroom under lights. Haven't seen crazy regrowth but my shed slowed noticeably so could be worth it if youre already committed to fin, worst case you waste some money and your hair looks the same.