The Russian stack — Semax + Selank, how are you running it?

S
Joined 2025
97 posts
3/16/2026 · 1217 views

Planning to run Semax 600 AM + Selank 600 when anxiety spikes (2-3x/week). Have seen three schools of thought:

  1. Same-session dose both peptides back-to-back. Quickest but you have saline drip city.
  2. Separate by 15-30 min to avoid intranasal dilution.
  3. Alternate days (Semax days and Selank days) to avoid blunting either.

Who's running what, and what did you settle on?

Growth + recovery
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 250 mcg · 2x/day · sub-Q

10 Replies

S
Joined 2026
47 posts
3/16/2026

Option 2 for me. 20 min between them. Back-to-back I lose half the second peptide out the front of my nose. Alternate days felt like I was gaming my anxiety schedule which is dumb because it doesn't schedule itself.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
S
Joined 2026
36 posts
3/17/2026

Separate by 15 min, different nostril for each. Might be placebo but I don't like the idea of two peptides competing for the same epithelial real estate.

P
Joined 2026
25 posts
3/17/2026

Same nostril, 15 min apart, tilt your head after each. The 'different nostril' thing might matter less than people think — the intranasal absorption area is much bigger than the part any spray actually hits.

N
Joined 2026
20 posts
3/18/2026

I ran alternate days for 2 months and stopped because it turns out my anxious days and my low-focus days aren't always the same days. The stack now is Semax every AM, Selank on demand. Works better.

S
Joined 2025
97 posts
3/19/2026

@hexaclinic that's fair. I was partly pattern-matching to the 'CJC/Ipa' framing where two really do combine. Different situation here.

Growth + recovery
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 250 mcg · 2x/day · sub-Q
H
Joined 2025
212 posts
hexaclinicContributor
3/19/2026

Consider also that the 'Russian stack' as marketed is a vibe, not a pharmacologically coordinated protocol. They're two different peptides doing different things. Run them based on what each of them does for you, not because they sound good as a pair.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
W
Joined 2026
24 posts
3/21/2026

Saving. Was going to run these both back-to-back because that's what the YouTube video showed. Thanks for the detail on separation.

C
Joined 2026
71 posts
3/24/2026

'They're two different peptides doing different things, run them for what they actually do' should be pinned on every stack thread in this sub.

G
Joined 2026
40 posts
4/23/2026

Been running Semax daily in the AM for focus and Selank whenever the anxiety actually hits, not on a schedule. Tried the same-session thing first and yeah, just felt like I was snorting saline. The separation thing made more sense to me than alternate days since like hexaclinic said, you're not trying to create some synergy that isn't there. Semax handles the mental clarity piece, Selank handles the panic response, they're doing their own jobs. YMMV but I'd skip the marketing narrative and just dose based on what you actually need that day.

A
Joined 2026
31 posts
acl_againMember
17d ago

Yeah this thread just saved me because I was definitely gonna do the back-to-back thing. Makes sense that they're not some magic combo, just two separate tools. Been lurking a lot and it seems like half the "stacks" people talk about are just two things that happen to exist at the same time lol. Gonna try Semax daily for the focus part first, then add Selank only when I actually need it instead of forcing a schedule. Thanks for the reality check hexaclinic.

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