Humanin — anyone actually running this or is it too hard to source?

H
Joined 2026
23 posts
3/31/2026 · 455 views

Mitochondrial-derived peptide like MOTS-c but less hyped, less available, less characterized. Curious if anyone here has tried it, what protocol, what they noticed.

5 Replies

M
Joined 2026
41 posts
motsc_opsMember
4/1/2026

I've sourced once. Very limited suppliers. Ran 5mg 2x/week for 6 weeks. Subjective energy similar to MOTS-c but I can't separate it from the MOTS-c baseline I was on. Would want to isolate but sourcing is a hurdle.

H
Joined 2025
212 posts
hexaclinicContributor
4/3/2026

Preclinically interesting. Clinically: essentially unexplored in healthy people. If you can source clean material and run a careful pulse it's worth a try but don't expect published human data for a while.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
S
Joined 2026
117 posts
4/4/2026

Until there's human PK data I'd be very cautious on dose. The rodent-to-human extrapolation in this family is not straightforward.

T
Joined 2026
30 posts
4/7/2026

Interested but waiting. MOTS-c has enough reach for my purposes for now and I'd rather see someone else characterize humanin more first.

S
Joined 2026
18 posts
15d ago

Yeah sourcing is the real bottleneck here, not even gonna pretend I know where to get clean stuff. The thing that gets me is we have like decades of mitochondrial research showing these peptides matter but the moment something leaves the lab it's just vibes and anecdotes. I had a whole thing where I was comparing energy levels across different stacks last year and honestly the placebo effect was so strong I gave up trying to tease apart what actually did anything. If you do find a source and run it lmk what batch consistency looks like because that's probs the real question anyway.

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