Semax intranasal 10-week log — cognitive and mood tracking

S
Joined 2026
47 posts
1/16/2026 · 3340 views

Been meaning to run a proper Semax log for a while. I'm a software engineer, desk job, high cognitive load. Lately I've been struggling with sustained focus on harder problems — I can do 30 minutes then lose thread.

Goal: see if Semax moves my subjective focus/mood numbers in a repeatable way, and whether it survives a washout.

Baseline tracking (2 weeks pre-cycle):

  • Focus self-score 1-10, same time each day (11am): 6.2 avg
  • Mood 1-10 (11am): 6.8 avg
  • Task-switching frustration 1-10: 6.0 avg
  • Sleep quality 1-10: 7.1 avg
  • Anki retention on a tough deck: 82%

Stack:

  • Semax intranasal, 1mg/day AM, 10 weeks
  • No other new variables, no changes to caffeine/sleep/exercise

Will post every 2 weeks.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal

14 Replies

S
Joined 2026
36 posts
1/30/2026

Semax is the one that gives me a legitimate 'clicked into gear' feeling. Selank is more about anxiety for me.

S
Joined 2026
47 posts
1/30/2026

Week 2: focus 7.4 avg, mood 7.3 avg, task-switch 5.1, sleep 7.0, Anki 85%. Noticeably easier to sit down and get into a flow state in the morning.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
P
Joined 2026
17 posts
1/31/2026

Good that you have a 2-week baseline. Placebo is strong on cognitive compounds.

S
Joined 2026
47 posts
2/13/2026

Week 4: focus 7.6, mood 7.4, task-switch 4.8, sleep 7.2, Anki 87%. Holding the improvement. Friends noticing I seem 'on' in the morning more than before.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
N
Joined 2026
20 posts
2/27/2026

The stressful-week dip is common. Semax doesn't override the rest of your life, it just raises the baseline a bit.

S
Joined 2026
47 posts
2/27/2026

Week 6: focus 7.3, mood 7.2, task-switch 5.2, Anki 85%. Slight regression this week, I think because work was unusually stressful. Hard to separate signal.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
S
Joined 2026
47 posts
3/13/2026

Week 8: focus 7.7, mood 7.3, task-switch 4.5, Anki 88%. Back to the trend. Started testing whether dosing late afternoon messes with sleep — no, but I also noticed a late dose does nothing as far as I can tell.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
S
Joined 2026
47 posts
3/27/2026

Week 10 final + washout plan: focus 7.5, mood 7.3, task-switch 4.7, Anki 87%. Dropping to nothing now for 2 weeks and will re-test to see if it sticks.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
P
Joined 2026
25 posts
3/28/2026

The washout re-test is the actual payoff of this log. Most people skip it.

S
Joined 2026
47 posts
4/3/2026

Washout week 1: focus 7.0, mood 6.9, task-switch 5.5, Anki 84%. Noticeable slip already.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
S
Joined 2026
47 posts
4/10/2026

Washout week 2: focus 6.6, mood 6.9, task-switch 5.8, Anki 83%. Back to near-baseline on focus and Anki, mood held a bit.

Conclusion: for me, Semax produced a modest but clearly positive bump on focus and retention that did NOT survive washout. Mood was a smaller effect. Going to resume at 1mg/day as a workday tool, skip weekends.

Focus stack
  • Semax · 600 mcg · AM intranasal · intranasal
  • Selank · 250 mcg · as needed · intranasal
L
Joined 2025
37 posts
4/11/2026

Gold standard on the cognitive side. Adding to the example list.

Research cycle
  • MOTS-c · 10 mg · weekly · sub-Q
  • 5-Amino-1MQ · 100 mg · daily AM · oral
C
Joined 2026
71 posts
4/12/2026

I'll give it to you — this is about as well-designed a self-trial as you can do on a cognitive compound without a blinded placebo. Nicely done.

H
Joined 2025
212 posts
hexaclinicContributor
5/3/2026

nice log man, the washout data is legit. makes me wonder if stacking it with something like NA-Semax would hold the gains longer or if youre just fighting biology at that point. also unrelated but i've noticed most desk workers who complain about focus loss are actually just dehydrated, so maybe worth checking if you're actually drinking water lol. anyway respect for the rigor here, too many people just vibe check their compounds and call it a day.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
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