Cagri + Sema cycle, week 8 — combo GLP-1 log

C
Joined 2026
19 posts
cagrisemaMember
2/15/2026 · 2805 views

Running cagrilintide + semaglutide combo. 38F, 5'6", starting 182 lb, goal 150. I've done sema solo before, hit a wall at around 165. Wanted to see if adding cagri breaks the plateau behavior.

Stack:

  • Semaglutide 0.5mg/week
  • Cagrilintide 0.5mg/week (same day, different site)
  • 16 week plan

Baseline: 182.0 lb, waist 36", A1c 5.5.

10 Replies

S
Joined 2026
28 posts
3/1/2026

Cagri has this weirdly calming effect on the stomach side. I know it sounds backwards but a lot of people report the combo is gentler than sema alone at equivalent weekly weight-loss pace.

Week 14
  • Semaglutide · 1.7 mg · weekly · sub-Q
C
Joined 2026
19 posts
cagrisemaMember
3/2/2026

Week 2: 178.6 lb. Nausea is there but honestly less than my solo sema first few weeks, which surprised me. Appetite crushed.

C
Joined 2026
19 posts
cagrisemaMember
3/15/2026

Week 4: 174.2 lb. Down 7.8 total. No real side effects currently other than I have to remind myself to eat. Energy holding.

C
Joined 2026
19 posts
cagrisemaMember
3/16/2026

Yeah I'm force-feeding protein shakes morning and evening. Getting to 130g most days. Not great but above the drift line.

F
Joined 2026
30 posts
3/16/2026

Post protein every day if you want to keep muscle. That's where the combo gets people — so little hunger that they slide into 60g/day.

C
Joined 2026
19 posts
cagrisemaMember
20d ago

Week 6: 170.1 lb. Went below the point where I stalled on sema solo, which is the data point I came for. Pace holding at ~2 lb/week.

P
Joined 2026
36 posts
19d ago

Blowing through the prior plateau is the whole pitch for the combo. Nicely done.

C
Joined 2026
19 posts
cagrisemaMember
6d ago

Week 8: 167.8 lb. 14.2 lb down in 8 weeks on a very tolerable dose. Will update at week 12.

S
Joined 2026
36 posts
slow_loseMember
5d ago

Don't bump doses unless the pace stalls. 0.5/0.5 is getting you what you came for.

R
Joined 2026
26 posts
5d ago

Following this one. The combo logs are rarer than I'd expect.

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