Cagri + Sema cycle, week 8 — combo GLP-1 log

C
Joined 2026
21 posts
cagrisemaMember
2/15/2026 · 2845 views

Running cagrilintide + semaglutide combo. 38F, 5'6", starting 182 lb, goal 150. I've done sema solo before, hit a wall at around 165. Wanted to see if adding cagri breaks the plateau behavior.

Stack:

  • Semaglutide 0.5mg/week
  • Cagrilintide 0.5mg/week (same day, different site)
  • 16 week plan

Baseline: 182.0 lb, waist 36", A1c 5.5.

11 Replies

S
Joined 2026
33 posts
3/1/2026

Cagri has this weirdly calming effect on the stomach side. I know it sounds backwards but a lot of people report the combo is gentler than sema alone at equivalent weekly weight-loss pace.

Week 14
  • Semaglutide · 1.7 mg · weekly · sub-Q
C
Joined 2026
21 posts
cagrisemaMember
3/2/2026

Week 2: 178.6 lb. Nausea is there but honestly less than my solo sema first few weeks, which surprised me. Appetite crushed.

C
Joined 2026
21 posts
cagrisemaMember
3/15/2026

Week 4: 174.2 lb. Down 7.8 total. No real side effects currently other than I have to remind myself to eat. Energy holding.

C
Joined 2026
21 posts
cagrisemaMember
3/16/2026

Yeah I'm force-feeding protein shakes morning and evening. Getting to 130g most days. Not great but above the drift line.

F
Joined 2026
30 posts
3/16/2026

Post protein every day if you want to keep muscle. That's where the combo gets people — so little hunger that they slide into 60g/day.

C
Joined 2026
21 posts
cagrisemaMember
3/29/2026

Week 6: 170.1 lb. Went below the point where I stalled on sema solo, which is the data point I came for. Pace holding at ~2 lb/week.

P
Joined 2026
46 posts
3/30/2026

Blowing through the prior plateau is the whole pitch for the combo. Nicely done.

C
Joined 2026
21 posts
cagrisemaMember
4/12/2026

Week 8: 167.8 lb. 14.2 lb down in 8 weeks on a very tolerable dose. Will update at week 12.

S
Joined 2026
40 posts
slow_loseMember
4/14/2026

Don't bump doses unless the pace stalls. 0.5/0.5 is getting you what you came for.

R
Joined 2026
30 posts
4/14/2026

Following this one. The combo logs are rarer than I'd expect.

C
Joined 2026
28 posts
15d ago

Week 8 at 167.8 is solid. I ran sema solo for like 4 months and totally hit that wall around 166-168, couldn't budge past it no matter what I did with diet or cardio. Curious if you're gonna stick with the same doses or if you're thinking about adjusting down the road. The fact that cagri is letting you keep momentum where sema alone just stopped is probably the real story here.

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