Retatrutide log — stopping early, side effects (week 5)
30 posts
Starting a reta log. 45F, 5'4", 198 lb. Want to lose 45 lb. Have tried sema (worked but plateaued at 178) and tirz (worked but plateaued at 172). Going full experiment with reta.
Starting dose: 2mg/week. Plan to titrate by 1mg every 4 weeks.
12 Replies
40 posts
Reta at 2mg hits harder than sema at 1mg or tirz at 5mg for most people. Titrate slower than you think.
30 posts
Week 1: 195.2. Dropped 2.8 lb in a week which is more than I ever saw on the others. Nausea is real, about 48h.
30 posts
Week 2: 191.0. Nausea stuck around longer than last week — more like 72h this time. Stomach cramping at 4am two nights in a row.
10 posts
The 4am cramping is not a normal side effect profile. Consider dropping to 1mg.
30 posts
Week 3: 188.1. Dropped to 1mg as suggested. Cramping gone after the lower dose, nausea back to mild.
40 posts
RHR bump on reta is real for a minority. It's an off-target effect. If it doesn't come down this week I'd stop.
30 posts
Week 4: 186.8. Heart rate elevated for a few days (Oura showing RHR jumped from 62 to 74). That freaked me out.
30 posts
Week 5: RHR still 72. Not coming down. Stopping today. Down 11.2 lb in 5 weeks but this isn't worth messing with my cardiovascular system for. Will probably go back to tirz microdose for maintenance.
212 posts
Making the right call. Posted early-stop logs are more valuable than a lot of successful ones.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
53 posts
Exactly the right call and thanks for posting it. This is what the 'stop criteria' question in the template is for.
- Sermorelin · 200 mcg · 5x/wk AM · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
30 posts
Reta isn't for everyone. You'll probably do great on tirz micro for hold. Good luck.
36 posts
good call stopping, RHR creeping up like that is legit a red flag. sema and tirz have way more data on the safety side anyway so you're not losing much by rotating back. plus you already know what dose range works for you on tirz so you can probably dial in maintenance pretty quick instead of chasing another compound