Ipamorelin vs Hexarelin — when would you actually pick hexarelin

I've used hexarelin for 2-week pulses during rehab blocks. Works well. I never run it longer than that. Desensitization is very real and you lose the tool.

Short acute-injury window is exactly where I reach for hexarelin. 2-3 weeks at 200mcg 2x, on top of a healing compound like BPC. After that I rotate out. Past week 3 the cortisol bump shows up and the gain is smaller than the cost.

Ipa non-responders are a real subset. My wife is one — Ipa at 300mcg did almost nothing for her sleep or recovery. Hexarelin at 150 was obvious. Some receptor variation explains it.

The prolactin bump on hexarelin is worth flagging for men prone to prolactin-sensitive sides. Doesn't happen to everyone but when it does you notice. Low-dose caber is an option but at that point your stack is getting convoluted.

The Raun 1998 data showed hexarelin's pulse is ~2-3x larger than ipamorelin at matched doses. The receptor tachyphylaxis kicks in harder though, so AUC at week 4 converges.

Used hexarelin for 3 weeks post-op on my rotator. No ipa on top. Pulse felt very strong, sleep was deep the first week. Week 3 it was clearly waning. Rotated to ipa + CJC after. Strategy worked well.

Hexarelin for short bursts, ipa for maintenance. That's my playbook.

The honest answer to 'when is hexarelin worth it' is 'when your protocol has a specific 2-3 week window where you want a maximum pulse.' Outside that window, the cost-benefit flips.

Old-head here, hexarelin was the default before ipa hit the scene. The reason ipa won isn't that hexarelin stopped working — it's that clean pulses with no sides are easier to sustain over long cycles. For a 3-week hammer, hex still has a place.

Great responses, about where my priors were. Summary: hexarelin is a specialty tool for short windows, Ipa is the workhorse. Anyone running hexarelin for 4+ weeks is probably leaving value on the table.