GHK-Cu — actual use cases beyond skin stuff
46 posts
GHK-Cu gets a lot of skincare buzz but the systemic use cases are less discussed. In the literature it shows up for wound healing, anti-fibrotic effects, hair regrowth, possibly inflammation modulation.
Anyone using GHK-Cu systemically (Sub-Q or IM) for: chronic inflammation, injury recovery, hair, or anti-aging? What doses and outcomes?
I'm considering adding 2mg 3x weekly Sub-Q to a recovery stack but the signal-to-noise on 'it works' is low on forums elsewhere.
10 Replies
94 posts
I've used GHK-Cu locally for scar remodeling (post-surgical) with good results. Systemic I've tried once, no notable effect at 2mg 3x. Could have been too low a dose, I don't know.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
205 posts
GHK-Cu systemic is niche for good reason — most of the impressive effects are local/dermal. Systemic dose-response is poorly characterized. 2mg 3x weekly Sub-Q is a reasonable experimental dose but don't expect BPC-tier results.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
17 posts
Topical GHK-Cu on my achilles insertion (cream formulation) seemed to help more than systemic anything. Local delivery is where this compound shines.
50 posts
Peri-lesional GHK-Cu injection during a rotator cuff rehab felt different — the tissue around the lesion seemed to 'settle' faster. Hard to quantify. For systemic anti-inflammatory goals I'd stick with BPC.
- BPC-157 · 250 mcg · 2x/day local · sub-Q
- TB-500 · 2 mg · weekly · sub-Q
71 posts
The systemic GHK-Cu data in humans is mostly from topical pharmacokinetic studies and in vitro work. Claims of 'systemic anti-aging effects' are extrapolations. Healthy skepticism warranted.
46 posts
Fair. Gonna scale my experiment to topical peri-injury use only. Not going to chase systemic.
25 posts
Has anyone used it for hair? I've seen the Pickart research cited for that.
94 posts
@curious_catL topical for hair is a defensible use. Systemic for hair is not well-supported. Topical scalp applications with a quality carrier are where the hair use case lives.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
71 posts
Net: GHK-Cu is a local/topical tool. Systemic use case is weak. Good thread for keeping expectations calibrated.
- BPC-157 · 500 mcg · 2x/day · sub-Q
- GHK-Cu · 2 mg · nightly topical · topical
16 posts
Learning a lot from these 'calibrate your expectations' threads. Thanks all.