Humanin at 5mg 2x/week — anyone actually tracking anything on this

H
Joined 2026
22 posts
3/9/2026 · 1494 views

Humanin is in the mitochondrial longevity bucket. Dosing is all over the map in forum reports. What's your protocol and are you measuring anything specifically?

5 Replies

T
Joined 2026
26 posts
3/10/2026

Adding humanin 5mg 2x to my longevity stack starting next month. Planning to track IGF, HOMA-IR, fasting glucose at baseline and 12 weeks. Will report.

M
Joined 2026
32 posts
motsc_opsMember
3/11/2026

Humanin evidence is mostly preclinical. Subjective reports of 'metabolic quieting' on forum but nothing rigorous. Worth tracking carefully if you run it.

N
Joined 2026
31 posts
3/12/2026

Pairs well with MOTS-c on paper. Haven't run together yet.

C
Joined 2026
71 posts
3/13/2026

Humanin human data is extraordinarily thin — a handful of observational papers on circulating levels vs age/disease. Therapeutic administration data is essentially zero. Treat it as an experimental compound with correspondingly low confidence.

P
Joined 2026
50 posts
3/14/2026

If you're going to run it, at least spend $80 on a HOMA-IR and hs-CRP pre/post. Without markers you're running a vibes protocol.

Sign in to reply.