Humanin at 5mg 2x/week — anyone actually tracking anything on this

Adding humanin 5mg 2x to my longevity stack starting next month. Planning to track IGF, HOMA-IR, fasting glucose at baseline and 12 weeks. Will report.

Humanin evidence is mostly preclinical. Subjective reports of 'metabolic quieting' on forum but nothing rigorous. Worth tracking carefully if you run it.

Pairs well with MOTS-c on paper. Haven't run together yet.

Humanin human data is extraordinarily thin — a handful of observational papers on circulating levels vs age/disease. Therapeutic administration data is essentially zero. Treat it as an experimental compound with correspondingly low confidence.

If you're going to run it, at least spend $80 on a HOMA-IR and hs-CRP pre/post. Without markers you're running a vibes protocol.

ran 5mg 2x weekly for like 8 weeks last year and honestly didn't notice much beyond what my other stuff was already doing. tracked fasting glucose and it was stable but that could've been diet/exercise. the real issue is you're basically injecting based on mouse data and a handful of old papers on people who were already sick, so like, manage expectations accordingly

yeah im running it now at 5mg weekly and doing fasting glucose + insulin before and after. honestly the main appeal for me is just the mitochondrial angle, not expecting to feel anything. humanin's one of those where if you're waiting for subjective effects you're gonna be disappointed