NAD+ Sub-Q vs IV — efficacy gap is real or imagined

Sub-Q at 100mg 2x/week covers general longevity use. IV is overkill unless you're running clinical-dose protocols for addiction or neurodegenerative stuff.

Sub-Q is slower release and you avoid the acute IV flush. For chronic support it's arguably better. For acute high-dose loading, IV wins.

PK data for Sub-Q NAD+ is limited but extrapolating from pyridine nucleotide class, Sub-Q gives a broader AUC with lower peak vs IV. For longevity use case, probably equivalent or better.

Thanks all. Going to stay Sub-Q. The IV clinics charge 3-5x for a marginal acute difference that isn't the use case I need.