GHRP-2 vs GHRP-6 — and when appetite stimulation is a feature
73 posts
GHRP-6 is infamous for ravenous hunger. GHRP-2 has some appetite effect but way less. Both are older GHRP compounds that have been partially displaced by Ipa and Hexarelin.
Where GHRP-6 actually wins: underweight populations or people trying to bulk who can't eat enough. The hunger isn't a side effect, it's the point. Lean gainers who get full at 2800 kcal will find GHRP-6 turns them into 4000 kcal eaters effortlessly.
GHRP-2 is a middle ground — decent pulse, mild appetite bump, slightly more prolactin than Ipa.
When does this matter in 2026? Almost never because Ipa is better for most people. But if you're a skinny lifter trying to reach caloric targets, GHRP-6 has a role Ipa literally can't fill.
- BPC-157 · 500 mcg · 2x/day · sub-Q
- GHK-Cu · 2 mg · nightly topical · topical
6 Replies
38 posts
GHRP-6 for the underweight lifter is underrated. I had a client (natural, lifelong skinny) go from 147 to 162 in 14 weeks on GHRP-6 100 mcg 3x daily because he finally could eat enough. Ipa wouldn't have done that.
212 posts
Correct take. GHRP-6 is niche, not obsolete. The feature is appetite. If that's what you need, use it. If not, Ipa is better.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
97 posts
GHRP-2's prolactin bump is smaller than hex but bigger than Ipa. For comparable GH pulse it's still worse than Ipa in 2026 in almost every scenario.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
21 posts
Cost consideration — GHRP-2 and GHRP-6 are cheaper than Ipa still. For someone budget-constrained, GHRP-2 at moderate dose is a reasonable entry point.
22 posts
I've been on GHRP-6 + CJC no-DAC for bulk. Appetite is the whole game at 45. This is working where Ipa didn't.
13 posts
GHRP-6 appetite thing is real but people sleep on the actual mechanism here. It's not just hunger signals, it's literally lowering your satiety threshold through ghrelin mimicry. If you're tracking calories and macros properly (and most people aren't) you'll see the effect show up in your logs, not just feeling "kinda hungry." The issue is everyone talks about this subjectively when it's actually measurable. You can run pre and post labs to confirm ghrelin elevation, track appetite hormones if you're serious about it instead of just saying "yeah bro I ate more.