'Blue skin' from GHK-Cu — is this a real risk or Reddit lore

F
Joined 2026
35 posts
1/11/2026 · 725 views

Keep seeing comments like 'be careful or you'll turn blue from the copper.' Is that a real thing from topical GHK-Cu, or are people confusing it with the argyria-style stories from oral colloidal silver / high-dose IV copper?

I assume topical doses of GHK-Cu are orders of magnitude too low to cause systemic copper accumulation but I want to be sure before I commit to daily use.

4 Replies

T
Joined 2025
58 posts
theoreticRegular
1/11/2026

Myth. Topical GHK-Cu at cosmetic concentrations delivers micrograms of copper at most. You'd need sustained high-dose IV copper or serious oral over-supplementation to get systemic copper toxicity. Not a real risk here.

Longevity
  • Epithalon · 10 mg · 10d on / 80d off · sub-Q
  • MOTS-c · 5 mg · 2x/wk · sub-Q
  • 5-Amino-1MQ · 150 mg · daily · oral
D
Joined 2025
119 posts
dr_doubtRegular
1/12/2026

Argyria (blue skin from silver deposition) is a real condition and gets confused with 'copper will turn you blue.' Different metal, different mechanism, and even the copper version requires doses you can't hit topically.

H
Joined 2025
205 posts
hexaclinicContributor
1/13/2026

You can temporarily stain skin blue-green if you apply a very concentrated GHK-Cu solution and it oxidizes on the skin. That washes off. Not the same thing as metal deposition.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
F
Joined 2026
35 posts
1/14/2026

Good to know. Proceeding with 0.1% serum daily.

Sign in to reply.