GHK-Cu into the microneedling channels — is this a real synergy
20 posts
Dermatologists sometimes apply GHK-Cu serum after microneedling to push it into the channels. In theory this delivers the peptide to the dermis way more effectively than passive topical.
Anyone doing this at home with a dermaroller or dermastamp? How often is reasonable, and is there a concentration that's too high when you're effectively bypassing the barrier?
4 Replies
205 posts
Real synergy, with caveats. Microneedling creates ~0.5–1.5mm channels, and applying GHK-Cu immediately after gives you far better dermal delivery than passive diffusion. But: use a sterile serum only. DIY formulations with questionable preservation go from 'topical, probably fine' to 'bloodstream, definitely not fine' when you've just punctured your face.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
32 posts
I do it every 4 weeks with a 0.5mm roller and a cosmetic-grade preserved serum. Skin tolerates it. Don't go deeper at home.
36 posts
0.5mm max at home. Any deeper needs a provider. And don't use a DIY reconstituted serum with microneedling — this is the one case where you want the commercial stuff for sterility.
- Tesamorelin · 1 mg · daily AM · sub-Q