Biological age testing on peptides — Elysium vs TruDiagnostic

TruDiagnostic with DunedinPACE is what I use. The pace-of-aging metric is more stable test-retest than single-point epigenetic age. Elysium Index is fine but more expensive per draw with less clear advantage.

All the consumer epigenetic age tests share the underlying issue that at the individual level, changes smaller than 0.5-1 year are inside the measurement noise. Don't over-interpret small movements. Quarterly draws look noisy for exactly this reason.

I draw TruDiagnostic every 6 months rather than quarterly. At quarterly the noise dominates. At 6 months you start to see trend.

Epigenetic clocks are better than telomere tests. Still noisy. Best used for trend over years, not A/B testing specific protocols over weeks.

Ran TruDiagnostic for like 8 months now and honestly the noise floor is real. You're gonna see wild swings quarter to quarter that mean nothing. The DunedinPACE metric is solid but the absolute numbers are less important than the slope, and you need at least 3 data points before you can even call it a trend. If you're gonna spend the money anyway might as well do 6 month intervals and actually have something worth looking at instead of noise.

Yeah the 6 month interval thing makes sense, everyone saying quarterly is just noise checks out. I'm only 2 months into some longevity stuff so I'm prob gonna wait till like month 4-5 before I even do a first draw. Seems like there's no point dropping money on something that won't show real signal for a while anyway.