HRV tracking peptides — which ones move the needle?
26 posts
Oura user for 4 years. Tracking HRV nightly. I've got enough data now to look at what peptide cycles did what to my HRV baseline.
Clear positive signal:
- Epithalon cycles (+5-8ms during and after)
- BPC-157 during injury recovery periods (confounded with rest)
- MOTS-c 8-week cycles (+4-6ms)
Neutral / noisy:
- Semax / Selank (no HRV signature, effect is cognitive not autonomic)
- TB-500
- PT-141 (used too acutely to see)
Clear negative signal:
- CJC/Ipa combo pre-bed (-3-5ms, probably sleep architecture disruption)
- Tesamorelin during cycles
- Alcohol and peptides simultaneously (-10ms+, obviously)
Share yours. This kind of wearable data is underutilized in our community.
9 Replies
36 posts
Can confirm Epithalon HRV signature. +4 or so across cycles for me. Persists a few weeks post-cycle then fades.
33 posts
The CJC/Ipa HRV hit is worth a whole separate post. That plus the glucose issue is why I'm off them unless there's a specific injury reason.
45 posts
Reminder that Oura HRV nightly CV is around 10-15% for most users. You need sustained rolling averages (30+ days) to detect a real shift of a few ms. Single-night HRV posts are noise.
31 posts
NMN shifted mine up about 3ms on rolling average. Subtle but consistent. Dropped back on washout.
71 posts
Nice methodology here. Rolling averages, confounders called out, negative signals reported not hidden. More of this please.
36 posts
Going to start logging Epithalon cycles as pre/post HRV deltas systematically. Will post a year from now.
9 posts
Saving for my HRV experimentation notes. Exactly the kind of longitudinal take I was looking for.