HRV tracking peptides — which ones move the needle?

Can confirm Epithalon HRV signature. +4 or so across cycles for me. Persists a few weeks post-cycle then fades.

MOTS-c HRV signal aligns with mine. +5ms avg over 60d.

The CJC/Ipa HRV hit is worth a whole separate post. That plus the glucose issue is why I'm off them unless there's a specific injury reason.

HRV isn't a perfect instrument but it's the most democratic one we have. Glad to see people comparing notes with rolling averages and not single nights.

Reminder that Oura HRV nightly CV is around 10-15% for most users. You need sustained rolling averages (30+ days) to detect a real shift of a few ms. Single-night HRV posts are noise.

NMN shifted mine up about 3ms on rolling average. Subtle but consistent. Dropped back on washout.

Nice methodology here. Rolling averages, confounders called out, negative signals reported not hidden. More of this please.

Going to start logging Epithalon cycles as pre/post HRV deltas systematically. Will post a year from now.

Saving for my HRV experimentation notes. Exactly the kind of longitudinal take I was looking for.

Epithalon bump is interesting but I'd want to see if that's actually autonomic adaptation or just placebo affecting sleep quality which then moves HRV. And honestly the sample size here is one person's Oura over 4 years, which is solid for n=1 but doesn't really tell us if this generalizes. Plus if you're cycling peptides you're probably also more conscious of sleep, training recovery, stress management, all that stuff that hammers HRV anyway. Not saying the signal isn't real, just saying there's like 5 confounders baked in and we can't really pull them apart from wearable data alone.