Peptide timing around workouts — does it actually matter?
43 posts
Specific question: for non-GH peptides (BPC-157, TB-500, MOTS-c), does timing relative to training actually matter, or is this another case of people imposing structure on things where it doesn't exist?
My current habits:
- BPC-157: any time, usually AM.
- TB-500: any time, weekly.
- MOTS-c: 30-60 min pre-workout on lift days.
- CJC/Ipa (when I ran it): 30 min post-workout or pre-bed.
Is the MOTS-c pre-workout thing doing anything, or would I get the same effect dosing it with breakfast? I don't really know.
10 Replies
212 posts
For BPC-157 and TB-500 timing around training is mostly theater. They work on repair/healing, time course is days to weeks. MOTS-c pre-workout has some rationale (mitochondrial readiness) but it's weak.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
28 posts
TB-500 is dosed weekly-biweekly. The half-life and mechanism make workout timing completely irrelevant. Dose it whenever is convenient.
68 posts
GH peptide timing is the one that actually matters — you want the pulse in a fasting state, not post-meal. For everything else the obsession with timing is fan fiction.
- Epithalon · 10 mg · 10d on / 80d off · sub-Q
- MOTS-c · 5 mg · 2x/wk · sub-Q
- 5-Amino-1MQ · 150 mg · daily · oral
97 posts
Pre-bed for GH peptides vs morning has a real tradeoff: better sleep with GH pulse at night, worse glucose. Morning dosing flips that. Pick your poison.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
43 posts
Helpful. Dropping the pre-workout MOTS-c religion, going to AM dose with coffee like a normal person.
47 posts
The one peptide-timing thing I do defend is Semax 45-60 min pre-cognitively-demanding-work. That's the one time I swear I feel a delta. Everything else I'm with you.
- Semax · 600 mcg · AM intranasal · intranasal
- Selank · 250 mcg · as needed · intranasal
16 posts
On the GH peptide side, fasted-state dosing matters more than time-of-day per se. If you can't dose fasted because of schedule, a 2-hour window after last meal is the compromise.
- IGF-1 LR3 · 30 mcg · post-workout · sub-Q
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- MGF (PEG) · 200 mcg · post-workout · sub-Q
14 posts
People overweight timing because it's the variable they can control. The variables that actually matter (dose, cycle, quality of sleep, consistency) are harder to tinker with so timing becomes the ritual.
10 posts
Honestly the_architect_p nailed it. Timing is the easy knob to turn when you're already consistent with everything else, so people obsess over it. For BPC and TB-500 you're literally just flooding your system with recovery signals so timing doesn't do much. MOTS-c pre-workout is more of a "why not" than an actual edge if you're already pinning it daily. I'd rather see someone dial in sleep and actually eat enough protein than stress about whether they dose at 8am or noon.