Dihexa — is anyone actually running this safely
11 posts
Dihexa keeps coming up in nootropic circles as '7 orders of magnitude more potent than BDNF for synaptic formation.' That's the kind of claim that should make anyone pause. It's also never been in a human trial and the preclinical work is almost all from one lab.
I'm not planning to take it. I'm asking because I want to understand what 'running it safely' even means for a compound with no human data. Is it literally just 'low dose, hope for the best'?
4 Replies
46 posts
Mod reminder: we've had conversations about dihexa that crossed into encouraging unsupervised experimentation. Keep discussion to mechanism and risk framing, not 'here's how to dose it.'
- Sermorelin · 200 mcg · 5x/wk AM · sub-Q
- BPC-157 · 250 mcg · 2x/day · sub-Q
58 posts
The one-lab problem is the big flag. It's not that the work is bad, it's that nobody's replicated. For a compound this potent this would be Nobel territory if the claims held up independently. They haven't been tested independently.
- Epithalon · 10 mg · 10d on / 80d off · sub-Q
- MOTS-c · 5 mg · 2x/wk · sub-Q
- 5-Amino-1MQ · 150 mg · daily · oral
34 posts