BPC-157 for rotator cuff — 12 week log (FINISHED, wrap-up inside)

Week 1 update: no real change in pain yet, which is expected. Injections have been painless, no site reactions beyond a little redness that fades in an hour. Sleeping marginally better but honestly that's probably just the sling preventing me from rolling over.

How's the ROM feeling? Sometimes that moves before pain does in my experience.

ROM is the same but pain at end range is way down, interestingly. I can get further before it starts to complain, even though the actual stop point hasn't moved.

Following. Subq for shoulder is what I'd do too — local injection is overkill for partial tears like this. Curious to see how week 4 looks.

Week 2: night waking is down to 2-3 nights instead of 4-5. Pain at rest is maybe 2/10 now. Overhead reach still 6-7/10 if I push it but I don't push it. No side effects at all from the compound.

Nice. Went through something similar on the other side last year and the first meaningful shift for me was around week 3-4. Hang in there.

Week 3: slept through the night 5 nights out of 7. First time since October. Emotionally this is huge tbh. Pain with overhead reach still there but dialed back. Going to try an empty bar front raise next week just to benchmark.

Don't test it too early man. The temptation is real.

Week 4 check-in: sleep pain essentially gone. Woke once this week and it was because I tried to sleep on it directly (learning curve). Overhead reach pain down to 4/10. ROM has started to open up — measured with a broomstick and I'd say 10 degrees more ER than baseline. Not testing the press. Continuing same dose.

Good log. Good discipline on not testing the press. That's how reinjuries happen.

This is textbook. Keep doing exactly what you're doing.

Week 6: reassess time. Overhead reach 2/10 pain. ROM probably 90% of the other side. PT cleared me to start adding light loaded presses with empty bar next week. I'm going to keep BPC going through the press reintroduction and taper off at week 12.

Any thought to adding TB500 for the second half? Not saying you need to but some people stack the two for tendon work.

Honestly I thought about it but the rule of 'change one variable' says no. If this works it works, and I'll know BPC alone did it. If I add TB500 at week 6 I won't know.

This is the right instinct. Save TB500 for next time if you need it.

Week 8: empty bar press, 3 sets of 8, zero pain. Added 10 lb plates — still zero pain. This is wild. Going to stay conservative on load but this is the first time I've pressed anything in six months without wincing.

Love to read this. Been nursing a knee thing and this thread is convincing me to actually try the protocol instead of just reading about it.

Week 10: up to 95 lb for 3x8. No pain during, no pain after, sleeping fine. Starting to wonder if I'm imagining the injury was ever there. Going to finish the full 12 weeks as planned, no reason to cut short.

FINAL — Week 12 wrap-up:

Starting → ending:

• Rest pain: 3/10 → 0/10
• Overhead reach pain: 7/10 → 0/10
• Night waking: 4-5x/week → 0x/week
• Overhead press: couldn't do empty bar → 115 lb for 3x8, clean
• ROM: missing 20deg ER → within 5deg of other side

Total cost: roughly $220 in compound, $30 in pins/bac water.

Side effects: none. Zero.

Would I do it again: absolutely. If I pull something on the other side I won't waste 8 weeks on PT alone before pulling this out.

Biggest lesson: 500mcg 2x subq is plenty. I was tempted to go higher and glad I didn't. Also, discipline on not loading early is probably as important as the compound itself.

Thanks to everyone who followed along. Closing this out.

Gold standard log. Going to link this from the template thread as an example.

Hell of a log. Thanks for closing it out properly, so many people just vanish.

Great work. This is what the forum is for.

Coming back to say thank you for this. Starting my own shoulder log next month and I'm going to follow your protocol almost exactly.