Sleep stack — MOTS-c + epitalon + pre-bed GH sec, real or overkill
22 posts
Running this for 8 weeks to see if I can push sleep metrics. Stack:
- MOTS-c 10mg weekly Sub-Q (started week 1)
- Epitalon 10mg daily for 10 days (weeks 5-6)
- CJC no-DAC 100 + Ipa 150 pre-bed (weeks 1-8)
Baseline Oura: deep 68min avg, REM 94min, HRV 42. Week 4 Oura: deep 84min, REM 112min, HRV 51.
Is the improvement from the GH sec alone, the epitalon (though it hadn't started yet), the MOTS-c systemic effect, or placebo? Trying to pull this apart.
11 Replies
40 posts
Run epitalon weeks 5-6 as planned, re-measure week 6-7. If deep/REM go up further or HRV climbs, attribute to epi. If flat, the GH sec is doing the work.
71 posts
GH sec pre-bed + sleep metrics is well-established. Epitalon sleep effect is supported by Russian literature but not well-replicated elsewhere. MOTS-c sleep is speculative. Your attribution order should follow the evidence weight.
73 posts
You're doing this the right way. Isolate the variable (epi) by running it in a window and comparing. Most people would add everything at once and never learn what's doing what.
- BPC-157 · 500 mcg · 2x/day · sub-Q
- GHK-Cu · 2 mg · nightly topical · topical
35 posts
NAD+ 100mg Sub-Q 2hr pre-bed is another sleep-active compound I'd rotate in eventually. Deep sleep bumps in my data. Consider for a subsequent cycle.
24 posts
The mitochondrial class (MOTS-c, humanin, NAD+) collectively seems to shift sleep architecture over months not weeks. Sleep is one of the downstream markers that moves last, in my experience.
16 posts
CJC/Ipa pre-bed is gonna be the driver here, that's just known. The epi and MOTS-c are probably doing something but its gonna take months to really see the signal. You're running it right tho, at least you'll know what the GH secretagogue baseline is doing.
53 posts
honestly the thing that gets me is how much of sleep quality is just sleep consistency and room temp, like i ran the exact same stack for like 6 weeks and didnt move the needle until i got blackout curtains and dropped the room to 62F, then suddenly my REM jumped stupid high. not saying your compounds aren't doing anything but id be way more curious about your sleep environment variables before assuming MOTS-c is the magic. that said the CJC/Ipa combo does seem to be the floor everyone agrees on, everything else is just fine tuning on top of that
- BPC-157 · 250 mcg · 2x/day local · sub-Q
- TB-500 · 2 mg · weekly · sub-Q