Using sema purely for cravings / metabolic — not primarily weight loss

0.15mg indefinitely here, same use case. Cravings evaporate. Lost 8lb and held it. If you don't want to lose weight you'll need to deliberately eat to maintenance — you'll just have to do it without the food noise pushing you. That's actually easier, not harder.

Recommend pulling full metabolic panel before and 90 days in. HbA1c, fasting glucose, fasting insulin, ApoB, hs-CRP. That's how you'll know if the use case is paying off beyond subjective craving reduction.

At your BMI, muscle preservation matters more, not less. If you drop even 5lb and it's lean, that's a meaningful hit. Eat protein, lift.

honestly this is the move. you're not chasing a number on the scale, you're fixing the underlying signal that's messing with your compliance. once the cravings actually shut up you'll realize how much mental energy you were burning just fighting them. and yeah the protein/lifting thing matters, but real talk most people at your stats who run sema end up eating MORE because suddenly food isn't screaming at them constantly. just track it for a month and adjust up if needed.

Real question though, are you tracking cravings subjectively or actually measuring something? Like a food log, macro adherence, number of times you reach for sweets per day. Because "cravings evaporate" feels good but if you're not measuring baseline vs 90 days you won't actually know if it's the sema or just placebo + the act of paying attention to your eating. The metabolic panel thing is solid but that doesn't tell you about the craving reduction specifically, which is the whole reason you're considering this.