Chronic tendinopathy that hasn't responded to anything — TB alone or stack?
50 posts
5 years of left patellar tendinopathy. Tried everything short of PRP and surgery: rehab (multiple cycles, eccentric protocols done properly), PT for months, dry needling, shockwave, BPC cycles (3 of them). All gave partial relief that didn't stick.
Considering a full TB-500 cycle alone to see if the systemic angle unlocks something BPC hasn't. Or I should stack with BPC again despite diminishing returns?
Partial response to BPC — not nothing, not a fix. Curious if people with similar 'BPC didn't finish the job' cases found TB did anything additional.
- BPC-157 · 250 mcg · 2x/day local · sub-Q
- TB-500 · 2 mg · weekly · sub-Q
5 Replies
205 posts
Chronic tendinopathy that's had 5 years of peptide and rehab is mechanically different from an acute tendinopathy. The collagen architecture has actually changed — it's disorganized and fibrotic. Peptides are better at acute repair than at reorganizing old scar-like tissue. Worth considering whether you're chasing the wrong tool.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q
31 posts
Chronic rotator. BPC-only got me 60% of the way. Adding TB didn't finish the job — PRP did. Not selling PRP, just reporting what moved a tendon that had resisted 3 years of everything else. TB helped the global feel but didn't fix the specific tendon.
17 posts
Chronic Achilles, similar profile. TB addition on top of BPC gave me maybe 10% extra. Not worth the money for that alone. Heavy slow resistance loading for 12 weeks did more than the peptides at that stage.
50 posts
Noted. Probably pivoting to PRP consult + keeping rehab brutal. Peptides have given what they can for this one.
- BPC-157 · 250 mcg · 2x/day local · sub-Q
- TB-500 · 2 mg · weekly · sub-Q