TB-500 pin site irritation — is this a vendor issue or am I pinning wrong?

L
Joined 2026
10 posts
13d ago · 424 views

Third pin of a TB cycle. Small red lump at the pin site, slightly warm, a bit itchy. Doesn't look infected — no spreading, no pus, no fever. But the same sites have been lumpy for 2-3 days after each pin.

BPC on the same schedule, same needles, same BAC water — never had this. TB-specific.

Dilution, vendor, or pin technique? Trying to narrow down.

4 Replies

T
Joined 2026
26 posts
11d ago

Seconded. The 1mL reconstitution on TB is a common cause of site lumps. Dilute more, pin more volume, problem usually disappears.

H
Joined 2025
205 posts
hexaclinicContributor
11d ago

Most likely the dilution. TB-500 is a higher-concentration pin by volume than BPC at typical reconstitution. If you reconstituted a 5mg vial with 1mL BAC, you're pinning dense peptide solution. Redo with 2mL BAC, pin 2x the volume for the same dose. Usually fixes the site reaction.

Q2 stack
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 500 mcg · 2x/day · sub-Q
S
Joined 2025
94 posts
10d ago

Also — TB does produce a mild local inflammatory response for some people independent of dilution. If re-diluting doesn't fix it within a pin or two, consider rotating to a different site region (flank vs abdomen) or slowing your push speed. Faster push = more local irritation.

Growth + recovery
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 250 mcg · 2x/day · sub-Q
L
Joined 2026
10 posts
8d ago

Re-dilution fixed it. 2mL BAC on the next vial, no lumps. Thanks.

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