Injection site rotation on tirze — abdomen vs thigh, does it matter?

S
Joined 2026
25 posts
22d ago · 894 views

New to tirze, week 3. Have been injecting abdomen exclusively. Is thigh equivalent or are there absorption / comfort differences?

3 Replies

C
Joined 2025
41 posts
21d ago

Both work. Abdomen tends to have slightly faster absorption due to higher vascularity, thigh is slower and more gradual. For weekly dosing this is clinically irrelevant — total AUC is basically the same. Use whichever is more comfortable.

S
Joined 2025
94 posts
20d ago

Rotate both. I do abdomen three weeks, thigh one week, cycle. Keeps any single area from getting lumpy / bruised. Also you'll want the flexibility if you ever develop an injection reaction in one area.

Growth + recovery
  • CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
  • Ipamorelin · 200 mcg · pre-bed · sub-Q
  • BPC-157 · 250 mcg · 2x/day · sub-Q
T
Joined 2026
44 posts
19d ago

Back of arm works too if you have someone to help. Not a daily option but a 'travel and don't want to expose abdomen' option.

Tirze cycle
  • Tirzepatide · 5 mg · weekly · sub-Q
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