Follistatin / FS-344 — is anyone really using this for hypertrophy?

Joined 2026
23 posts

1/16/2026 · 444 views

Follistatin gene therapy (AAV-FS344) has been floated in research for muscular dystrophy. The peptide analogs sold in the gray market are different things and the 'follistatin 344' vials out there are almost certainly not the gene therapy.

Anyone actually running peptide follistatin and seeing anything? My guess is the answer is 'no, it's a branding exercise' but I'm open to being corrected.

3 Replies

Joined 2025
119 posts

dr_doubtRegular

1/17/2026

The gene therapy is not the peptide. The peptide bioavailability is poor even if purity is good. 'FS-344' sold as a peptide is closer to a marketing SKU than a real research tool.

Joined 2025
58 posts

theoreticRegular

1/18/2026

Myostatin inhibition via peptide follistatin in humans: no good evidence. Real myostatin inhibitors that have shown muscle gain are all biologics in clinical trials, not this.

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Joined 2026
37 posts

recomp_rexMember

1/24/2026

Ran a full cycle of gray-market 'follistatin' and noticed nothing beyond the training gains I'd expect anyway. Waste of money for me.