Stalled 11 weeks at 1.7mg — dose hold, step up, or switch to tirze?
36 posts
Weight flat for 11 weeks on 1.7mg sema. Same diet, same training. 5lb range oscillation but no net loss. Three options: 1) hold and wait, 2) step to 2.4, 3) switch to tirzepatide. Has anyone switched from stalled sema to tirze and seen new loss?
4 Replies
31 posts
Before switching drugs: what's your actual kcal intake? An 11-week stall at any GLP-1 is usually 'calories crept up' more than 'drug stopped working.' Log everything for 14 days to scale, then decide.
44 posts
Switched at a similar stall point. Sema 1.7 -> tirze 7.5. Lost 11lb in the first 6 weeks on tirze. Dual mechanism (GIP+GLP-1) genuinely pulled where sema alone had plateaued. N=1 but it matches what others have reported.
- Tirzepatide · 5 mg · weekly · sub-Q
28 posts
I'd try a 2-week full break before switching. Sometimes receptors resensitize and the same dose works again after a pause. Cheaper than switching molecules.
- Semaglutide · 1.7 mg · weekly · sub-Q
205 posts
The 'stall' question almost always decomposes into: maintenance calories dropped with weight, and you haven't reduced intake to match. Your body at -50lb needs ~15-20% fewer kcal than at start. Drug suppressing appetite doesn't mean you're eating fewer calories than you burn at the new weight.
- CJC-1295 no DAC · 100 mcg · pre-bed · sub-Q
- Ipamorelin · 200 mcg · pre-bed · sub-Q
- BPC-157 · 500 mcg · 2x/day · sub-Q